Purpose: Evaluate the iridocorneal angle and anterior chamber depth (ACD) changes in eyes that underwent phacoemulsification surgery and in eyes that underwent phaco-vitrectomy with silicon oil as vitreous tamponade, and to compare results in both groups. Methods: We included a total of 30 eyes, of which 15 eyes underwent phacoemulsification surgery and 15 eyes phaco-vitrectomy procedure using silicon oil as vitreous tamponade. Iridocorneal angle and anterior segment depth postoperative changes were documented by using anterior segment Ocular Coherent Tomography (VISANTE-OCT). Basal images were taken and repeated 1 and 3 months after surgery. Results: We found in all cases a significant iridocorneal angle and anterior segment depth increase after surgery. However, those changes were not significant when comparing both groups. Conclusions: The use of silicon oil as vitreous tamponade does not modify the iridocorneal angle and anterior chamber depth.