In this paper we will discuss two different layout concepts which can be applied to rail-vehicle assembly factory. The existing system is based on the traditional flow line, and the suggested system is based on the fixed location layout. Simulation experiments indicate that the new system is better with respect to the throughput, manufacturing lead time and on-time delivery rate, and it is also robust with respect to the shortage rate, the variance of shortage time and the variance of production cycle time. The operating cost of the new system is smaller, and thus it is sustainable for the changes in manufacturing environments.